My initiative includes gearing up software systems for genome data, a case study with SAS (documentation). I provide an embedded version of Hardy-Weinberg equilibrium test in sas_snphwe.sas here and the plugin version is omitted though not unlike its Stata counterpart.
My earlier programs are as follows,
DISCORD
- full name: A power analysis of discordant sib pairs
- web: discord.zip
- source code language: SAS
- reference: Karwautz A., Rabe-Hesketh S., Hu X., Zhao J., Sham P., Collier D. A., Treasure J. L. (2001). "Individual-specific risk factors for anorexia nervosa: a pilot study using a discordant sister-pair design". Psychological Medicine, 31(2):317-29.
GEMINI
- full name: an analysis example for GEMINI, Cambridge
- description: QTL linkage analysis of selected samples: conditioning on trait values
- web: gemini.zip
- source code language: SAS
- reference: Sham, P. C., Zhao, J. H., Cherny, S. S., Hewitt, J. K. (2000). "Variance components QTL linkage analysis of selected and non-normal samples: conditioning on trait values". Genetic Epidemiology, 19(Suppl 1), 22-28.
GO
- full name: genomewide association analysis on binary and continuous traits
- description: A set of SAS programs written for genomewide association analysis
- web: go.zip
- source code language: SAS
- reference:Zhao, J. H., Luan, J. A., Tan, Q., Loos, R. F. J., Wareham, N. J. (2007). "[Analysis of Large Genomic Data in Silico: The EPIC-Norfolk Study of Obesity]{style=”FONT-SIZE: 12pt; FONT-FAMILY: ‘Times New Roman’; mso-fareast-font-family: SimSun; mso-ansi-language: EN-GB; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA”} . Submitted to ICIC'07.
QTLSIM
- full name: Power analysis of genome scanning for QTL
- [description: QTL sib-pair linkage analysis ]{lang=”FR”}
- web: qtlsim.zip
- source code language: SAS
- reference:Sham, P. C., Zhao, J. H. (2000). "The power of genome-wide sib pair linkage scans for quantitative trait loci using the new Haseman-Elston regression method". Gene Screen, 1, 103-106.
MTDT
- full name: multiallelic TDT
- descriptions: a set of programs for several multiallelic TDT (multiallelic TDT and power: Bradley-Terry/Sham-Curtis, Spielman-Ewens, Bowker's/Bickeboller)
- web: mtdt.zip
- source code language: SAS
Date last changed 19/10/2012