Variants which directly affect the coding sequence or the protein produced.
Examples
protein_altering_variants
#> [1] "coding_sequence_variant"
#> [2] "frameshift_variant"
#> [3] "frameshift_variant,NMD_transcript_variant"
#> [4] "frameshift_variant,splice_donor_region_variant"
#> [5] "frameshift_variant,splice_region_variant"
#> [6] "frameshift_variant,splice_region_variant,intron_variant"
#> [7] "frameshift_variant,start_lost,start_retained_variant"
#> [8] "frameshift_variant,stop_lost"
#> [9] "frameshift_variant,stop_retained_variant"
#> [10] "incomplete_terminal_codon_variant,coding_sequence_variant"
#> [11] "inframe_insertion"
#> [12] "inframe_insertion,NMD_transcript_variant"
#> [13] "inframe_insertion,splice_region_variant"
#> [14] "inframe_insertion,stop_retained_variant"
#> [15] "missense_variant"
#> [16] "missense_variant,NMD_transcript_variant"
#> [17] "missense_variant,splice_donor_region_variant"
#> [18] "missense_variant,splice_region_variant"
#> [19] "missense_variant,splice_region_variant,NMD_transcript_variant"
#> [20] "missense_variant,stop_retained_variant"
#> [21] "protein_altering_variant"
#> [22] "stop_gained"
#> [23] "stop_gained,frameshift_variant"
#> [24] "stop_gained,frameshift_variant,splice_region_variant"
#> [25] "stop_gained,inframe_insertion"
#> [26] "stop_gained,NMD_transcript_variant"
#> [27] "stop_gained,splice_region_variant"
#> [28] "start_lost"
#> [29] "start_lost,splice_region_variant"
#> [30] "start_lost,start_retained_variant"
#> [31] "stop_lost"
#> [32] "stop_lost,splice_region_variant"
#> [33] "stop_retained_variant"