A protein Quantitative Trait Locus toolkit
It seeds the following collection of data and utilities for pQTL analysis: 1. Articles linking functions for cis/trans classification, pQTL-gene plot, 2d/3d-plotly plots, forest plots among others available from gap1; 2. Query on genes, regions, and SNPs via PhenoScanner2, adding functionality for pQTL novelty check; 3. Downstream analysis such as colocalization, pQTL-Mendelian Randomization via TwoSampleMR3, mapping of UniProt IDs to other resources; 4. Bioconductor notes, and showcases of LocusZoom.js snakemake workflow.
Installation
The latest version of pQTLtools can be installed as usual:
1. Install from R
if (!requireNamespace("remotes", quietly = TRUE)) install.packages("remotes")
remotes::install_github("jinghuazhao/pQTLtools")